Sarah Pannell Wilson (portrayed by Lola Miller) visiting the gravesite of her relatives, was the sister of politically active A.J. Pannell.

German immigrant August Rolf (portrayed by Dave Clutter) witnessed the hanging of abolitionist John Brown.

Henry Stifel Schrader (portrayed by Jay Frey) was a lawyer and philanthropist who donated funds for the Schrader Environmental Center.

Civil War soldier Thomas H. Norton (portrayed by Roger Micker) was later the military mayor of Jackson, Mississippi, during Reconstruction.

Anna Hartley Little (portrayed by Gael Fincham) was the wife of Civil War ambulance manufacturer Arthur Little.

Gertrude Lamb (portrayed by Bekah Karelis) was the daughter of Daniel Lamb, one of the founders of the State of West Virginia.

Texana Jordan (portrayed by Laurie Ruberg) became the Art Director of Wheeling public schools.

Lydia Cromwell Hearne (portrayed by Judi Hendrickson was a homeopathics doctor who was a community and political activist.

Nellie Egerter Faris (portrayed by Kate Quinn) was the wife of noted Wheeling architect Frederick Faris.